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United States President Donald Trump has threatened to slap tariffs on Canadian and Mexican products in a month’s time. This will lead to retaliatory tariffs by Canada against the U.S.

In an economic context where trade relations are interdependent and highly integrated, this tariff war will likely trigger a complex series of cascading effects, affecting governments, businesses and citizens alike.

President Donald Trump holds a signed executive order on deregulation in the Oval Office of the White House on Jan. 31, 2025, in Washington, D.C.
(AP Photo/Evan Vucci)

As a doctor in the psychology of decision-making, I strive to understand why we find it so difficult to manage the major complex challenges of our time like this looming trade war, whether it’s climate change and its ensuing hazards, pandemics and health crises, social inequalities, economic crises or the unpredictable behaviour of financial markets.

My aim is to uncover possible solutions to help decision-makers — particularly elected politicians — make choices that will improve the situation rather than aggravate it or create new problems.

Politics is a good example of a complex environment, marked by many interacting factors. Unforeseen events and trajectories further accentuate this complexity, especially as the desired objectives can sometimes conflict.

On the other hand, access to information relevant to decision-making is often restricted. The quality of content varies considerably due to misinformation shared by various sources actively disseminating misinformation influenced by partisan motivations and ideological perspectives, alongside disinformation, which is deliberately biased — two phenomena that have proliferated in recent years.

The limits of cognition

Faced with the complexity of the real world, human beings — politicians and ordinary citizens alike — are limited in terms of decision-making, and the solutions they propose are often influenced by bias.

This includes the propensity to filter information and retain only what corresponds to our personal ideology, and to judge a problem in terms of reference values. This is common in politics.

An example is the $7 million subsidy granted by the Québec government last year to finance two pre-season games for the Los Angeles Kings.

Despite a barrage of criticism, the government defended the expense, arguing it was within the usual order of magnitude of the budget dollars allocated to these kinds of sporting event. Its defence was basically: “That’s what we’ve always done.”

Such flawed thinking leads to an excessive focus on immediate symptoms rather than causes, while encouraging the implementation of superficial solutions. This type of behaviour is essentially aimed at reducing complexity to an intelligible level. Indeed, research shows that beyond four or five related variables, human cognition has enormous difficulty predicting how a situation will evolve.

System thinking

There are no ready-made answers to complexity. However, certain avenues are emerging, one of which has been attracting the attention of researchers for a number of years: it’s called system thinking.

The scientific community is continuing its empirical assessments of whether system thinking is a genuine cognitive skill and how to develop it in a sustainable way — for example, through training (a bit like working out at the gym, but in a lab). But it could potentially enable us to better manage complex socio-political problems.

System thinking is essentially about looking at problems holistically; thinking about the consequences of consequences. In this case, it’s about anticipating the cascading effects that a 25 per cent tariff on Canadian products exported to the U.S. could have on Canada’s economy.

Economists say the direct consequence of these tariffs will be an immediate drop in sales and revenues for Canadian companies, primarily those dependent on exports to the United States.

Read more:
U.S. tariff threat: How it will impact different products and industries

Companies will make bold attempts to enter new markets, but this will entail additional development and logistics costs, at least in the short term.

Some may have to lay off employees and reduce work shifts, which will boost unemployment and compensation claims, because retraining workers takes time. This will put pressure on public finances.

Prime Minister Justin Trudeau addresses the media following the imposition of a raft of tariffs by U.S. President Donald Trump against Canada, Mexico and China.
THE CANADIAN PRESS/Justin Tang

The impact on suppliers

For other companies, it will mean adjusting production downwards, which will affect suppliers. Reduced order books — whether for raw materials, components or services — will amplify the impact of the tariffs on all stakeholders in the supply chain.

In turn, these companies could be forced to reduce their workforces, leading to a further rise in unemployment.

This will put further pressure on public finances.

Once the government has reached its threshold of tolerance to criticism — the point at which the political costs become too high electorally — it may choose to intervene by supporting certain sectors having difficulties, for example through subsidies or loans designed to temporarily maintain competitiveness and preserve jobs in sectors deemed strategic.

This will put considerable pressure on public finances.

Higher taxes ahead?

In any case, a tariff hike will damage trade relations, leading to an escalation of tensions and a new round of barriers, both tariff and non-tariff. A form of trade war, if you will.

You guessed it: this will put increased pressure on public finances.

Although simplistic in the face of the complexity of the real world, this brief thought exercise is useful, as it allows to practice anticipation: what will happen if the government is forced to increase spending? By using system thinking, you’ll be able to guess that taxes are about to rise.

Perhaps Trump would have made different choices if he had used system thinking and looked at the consequences of his actions. Considering the potential for inflationary pressures that threaten the American economy if he proceeds with tariffs against Canada in a month, any reasonable person would hesitate to impose them. Läs mer…

I sit on an ethics review committee at the Albany Med Health System in New York state, where doctors and nurses frequently bring us fraught questions.

Consider a typical case: A 6-month-old child has suffered a severe brain injury following cardiac arrest. A tracheostomy, ventilator and feeding tube are the only treatments keeping him alive. These intensive treatments might prolong the child’s life, but he is unlikely to survive. However, the mother – citing her faith in a miracle – wants to keep the child on life support. The clinical team is distressed – they feel they’re only prolonging the child’s dying process.

Often the question the medical team struggles with is this: Are we obligated to continue life-supporting treatments?

Bioethics, a modern academic field that helps resolve such fraught dilemmas, evolved in its early decades through debates over several landmark cases in the 1970s to the 1990s. The early cases helped establish the right of patients and their families to refuse treatments.

But some of the most ethically challenging cases, in both pediatric and adult medicine, now present the opposite dilemma: Doctors want to stop aggressive treatments, but families insist on continuing them. This situation can often lead to moral distress for doctors – especially at a time when trust in providers is falling.

Consequences of lack of trust

For the family, withdrawing or withholding life-sustaining treatments from a dying loved one, even if doctors advise that the treatment is unlikely to succeed or benefit the patient, can be overwhelming and painful. Studies show that their stress can be at the same level as people who have just survived house fires or similar catastrophes.

While making such high-stakes decisions, families need to be able to trust their doctor’s information; they need to be able to believe that their recommendations come from genuine empathy to serve only the patient’s interests. This is why prominent bioethicists have long emphasized trustworthiness as a central virtue of good clinicians.

Trust in the medical profession has been on a decline, especially among minorities.
FatCamera/ E+ via Getty images

However, the public’s trust in medical leaders has been on a precipitous decline in recent decades. Historical polling data and surveys show that trust in physicians is lower in the U.S. than in most industrialized countries. A recent survey from Sanofi, a pharmaceutical company, found that mistrust of the medical system is even worse among low-income and minority Americans, who experience discrimination and persistent barriers to care. The COVID-19 pandemic further accelerated the public’s lack of trust.

In the clinic, mistrust can create an untenable situation. Families can feel isolated, lacking support or expertise they can trust. For clinicians, the situation can lead to burnout, affecting quality and access to care as well as health care costs. According to the National Academy of Medicine, “The opportunity to attend to and ease suffering is the reason why many clinicians enter the healing professions.” When doctors see their patients suffer for avoidable reasons, such as mistrust, they often suffer as well.

At a time of low trust, families can be especially reluctant to take advice to end aggressive treatment, which makes the situation worse for everyone.

Ethics of the dilemma

Physicians are not ethically obligated to provide treatments that are of no benefit to the patient, or may even be harmful, even if the family requests them. But it can often be very difficult to say definitively what treatments are beneficial or harmful, as each of those can be characterized differently based on the goals of treatment. In other words, many critical decisions depend on judgment calls.

Consider again the typical case of the 6-month-old child mentioned above who had suffered severe brain injury and was not expected to survive. The clinicians told the ethics review committee that even if the child were to miraculously survive, he would never be able to communicate or reach any “normal” milestones. The child’s mother, however, insisted on keeping him alive. So, the committee had to recommend continuing life support to respect the parent’s right to decide.

Physicians inform, recommend and engage in shared decision-making with families to help clarify their values and preferences. But if there’s mistrust, the process can quickly break down, resulting in misunderstandings and conflicts about the patient’s best interests and making a difficult situation more distressing.

Moral distress in health care.

Moral distress

When clinicians feel unable to provide what they believe to be the best care for patients, it can result in what bioethicists call “moral distress.” The term was coined in 1984 in nursing ethics to describe the experience of nurses who were forced to provide treatments that they felt were inappropriate. It is now widely invoked in health care.

Numerous studies have shown that levels of moral distress among clinicians are high, with 58% of pediatric and neonatal intensive care clinicians in a study experiencing significant moral distress. While these studies have identified various sources of moral distress, having to provide aggressive life support despite feeling that it’s not in the patient’s interest is consistently among the most frequent and intense.

Watching a patient suffer feels like a dereliction of duty to many health care workers. But as long as they are appropriately respecting the patient’s right to decide – or a parent’s, in the case of a minor – they are not violating their professional duty, as my colleagues and I argued in a recent paper. Doctors sometimes express their distress as a feeling of guilt, of “having blood on their hands,” but, we argue, they are not guilty of any wrongdoing. In most cases, the distress shows that they’re not indifferent to what the decision may mean for the patient.

Clinicians, however, need more support. Persistent moral distresses that go unaddressed can lead to burnout, which may cause clinicians to leave their practice. In a large American Medical Association survey, 35.7% of physicians in 2022-23 expressed an intent to leave their practice within two years.

But with the right support, we also argued, feelings of moral distress can be an opportunity to reflect on what they can control in the circumstance. It can also be a time to find ways to improve the care doctors provide, including communication and building trust. Institutions can help by strengthening ethics consultation services and providing training and support for managing complex cases.

Difficult and distressing decisions, such as the case of the 6-month-old child, are ubiquitous in health care. Patients, their families and clinicians need to be able to trust each other to sustain high-quality care. Läs mer…

Imagine: You’re in charge of marketing for a major automaker, and your biggest competitor just recalled thousands of vehicles. Now customers are worried about the safety of cars like yours. Do you seize the moment and ramp up advertising to steal market share? Or do you pull back on ads, fearing that customers will connect your brand with the bad press?

For what marketing professors like me call “substitute brands,” this sort of dilemma pops up all the time. Whether it’s a product recall, a customer data breach or a scandal, bad news for one brand can shake customers’ confidence in an entire product category.

The big question: Should competitors respond by increasing or decreasing their advertising? And will these adjustments help or hurt sales?

At first glance, the answer might seem obvious. More ad spending should mean bigger market share, right? But the reality is more complex. In a recent study looking at how 62 car brands responded to a 2014 recall, my colleagues and I found that, on average, when a rival brand issues a recall, its competitors cut their ad spending in half. In other words, most brands treat a rival’s crisis as a threat rather than an opportunity.

And when we looked at the ads’ content, we saw something even more interesting. When a rival brand stumbled, we found substitutes boosted their price-focused advertising by 25% on average, likely in an attempt to attract deal seekers. At the same time, they cut quality-focused advertising by 71%, possibly to avoid drawing unwanted comparisons.

And here’s the kicker: This strategy works.

We found, on average, a rival’s recall raises a substitute’s monthly sales by 35.3% – and the more a brand pulls back on ad spending, the greater the effect. So, when a competitor falters, the best response isn’t necessarily to shout louder. Instead, the data suggests a smarter play: Spend strategically, focus on price messaging, and avoid drawing attention to quality comparisons.

How we did our work

To understand how brands respond when a competitor faces a crisis, we focused on a real-world case: Volkswagen’s recall of nearly half a million cars branded under the Sagitar model in October 2014. This provided the perfect opportunity to study how rival brands adjusted their advertising strategies.

The Volkswagen Sagitar is a version of the Jetta sold in China.
Volkswagen AG

We identified Sagitar’s substitute models – 62 other sedans in the A-class category, sold by more than 30 manufacturers – and collected data on sales and ad spending across 308 media markets in the months before and after the recall. We then did a statistical analysis, controlling for several other variables that could influence ad spending.

Why it matters

Prior research offers mixed guidance on how a substitute brand should adjust its ad spending after a rival’s marketing crisis. Anecdotal evidence from the automotive and consumer goods industries is also mixed. For example, after Samsung recalled its Galaxy Note 7 in 2016 due to faulty batteries, competing phonemakers aggressively ramped up their advertising in an attempt to increase their market share.

Similarly, in 2010, after a Toyota recall, General Motors offered incentives for Toyota owners to switch to a GM car. GM’s chief marketing officer positioned these incentives as GM’s way to meet car buyers’ desire for peace of mind, and reports suggest that GM’s and other rival carmakers’ sales increased following Toyota’s recall.

But my team’s research suggests that this sort of strategy might not be the best one. Sometimes, saying less actually says more.

The Research Brief is a short take on interesting academic work. Läs mer…

In a major escalation in the conflict in the eastern Democratic Republic of the Congo (DRC), rebels from the March 23 Movement – or M23 – have seized Goma, the capital city of North Kivu province. At least 773 people have been killed there since the M23 claimed to have won control on January 27, while rebels have also seized several other towns in North Kivu including Sake and Minova.

The rebels are now reportedly advancing towards Bukavu, the capital of South Kivu province. And Corneille Nangaa, who leads a rebel alliance of which M23 is the largest member, has vowed to march on the DRC’s capital in Kinshasa. Located 1,000 miles west of Goma, the capture of Kinshasa is unlikely. But the conflict still looks set to spread deeper into the DRC.

The speed of the M23 advance has taken many by surprise. The rebels captured Goma, a city of 2 million people, within just three days. But the conflict between the DRC and the M23, which takes its name from the 2009 date on which a deal was reached to end a revolt by members of the ethnic Tutsi group, has been grinding on intermittently for years.

Beginning in April 2012, when the M23 was formally created, the conflict has its roots in the same deep ethnic divisions that led to the Rwandan genocide in 1994. Following the genocide, where radical ethnic Hutus killed roughly 800,000 minority Tutsis, many Hutu extremists fled over the border into the DRC and settled in areas including North Kivu.

The M23 seeks to act as a self-defence force for Congolese Tutsis against discrimination both by the DRC and non-state actors. This includes targeting by the Democratic Forces for the Liberation of Rwanda, a Hutu-dominated rebel group that seeks to overthrow the Rwandan government. The group has in the past committed egregious acts of violence against civilians in North Kivu, including mass killings and sexual violence.

The M23 rebel group seized the city of Goma on January 27.
The Critical Threats Project at the American Enterprise Institute

The seizure of Goma is crucial for several reasons. First, it means that a sizeable and strategically important border province of the DRC is now in rebel hands. North Kivu is an active volcanic region that is rich in various minerals such as coltan, which is used in electronic equipment and the aerospace industry.

In May 2024 the M23 seized Rubaya, a key mining town that produces 15% of the world’s coltan. Since then, the group has generated considerable income from controlling mineral production and trade. Indeed, the Global Initiative against Transnational Organized Crime labels the agendas of armed groups in the eastern DRC as “profit-driven”.

Second, the capture of Goma has exacerbated inter-state tension between the DRC and Rwanda, raising the prospect of another inter-state war. News of the prized seizure came hours after the DRC’s foreign minister, Thérèse Kayikwamba Wagner, accused Rwandan troops of invading Congolese territory.

A UN report from 2013 found that Rwanda not only supports the M23 group, but actively commands its troops. UN experts now estimate that there are up to 4,000 Rwandan troops fighting alongside the M23 in the DRC. Rwanda has denied backing the M23 despite ample evidence to the contrary.

The Congolese government says Rwanda’s involvement is part of a ploy to exploit North Kivu’s vast mineral resources. In a report from December 2024, a panel of UN experts wrote that “fraudulent [mineral] extraction, trade and export to Rwanda” benefited both the M23 “and the Rwandan economy”. According to the Rwandan government’s own figures, the country exports far more gold than it mines.

And third, the escalating conflict will deepen an already grave humanitarian crisis in the region. In March 2024, the UN reported that the number of internally displaced people in the DRC had reached 7.2 million – one of the largest such crises in the world. It is estimated that over 6 million civilians in the east of the DRC are now facing high levels of food insecurity.

What next

The DRC and Rwandan governments have already gone to war on two previous occasions, once in 1996 and then again in 1998 in what turned into a more protracted five-year conflict. The first war was triggered by Rwanda’s invasion of the DRC to target anti-Rwandan rebel groups seeking refuge there. The war soon drew in other states and became known as Africa’s first world war. Since 1996, conflict in the eastern DRC has killed approximately 6 million people.

Yet despite this increased tension, there are hopes that a diplomatic solution can be reached. In the past, warring factions in the eastern DRC have agreed to temporary ceasefires following intensive mediation by international institutions such as the East African Community and the African Union, as well as neighbouring countries like Angola.

However, previous ceasefires have also been violated by both sides. And the stakes are arguably higher this time, with the DRC losing further territory and control over strategic cities to the rebels.

The Congolese government may be reluctant to accept peace conditions until it regains control over lost portions of territory. Indeed, the Congolese president, Félix Tshisekedi, has already snubbed prospective peace talks to establish a ceasefire.

Protesters attacked the embassies of Rwanda, France, Belgium and the US in Kinshasa, criticising the lack of international response to the rebel advance.
Chris Milosi / EPA

Western powers hold key leverage, and may be able to subdue the M23 insurgency. France has given its backing to the DRC government and has warned of the catastrophic humanitarian consequences should the situation deteriorate further.

The US and other major powers like the UK have also withdrawn state funding for Rwanda in the past over its support for the M23 insurgency. In 2013, for example, cuts to foreign aid forced Rwanda to scale back its support for the rebels, both through reduced military training and supply runs. The UK government has threatened to withdraw funding to Rwanda again following the M23’s capture of Goma.

Belgium, on the other hand, is leading calls for the EU to suspend a controversial minerals deal with Rwanda that boosts the bloc’s access to several elements in exchange for funding to help Kigali develop its mineral extraction infrastructure. When the deal was signed in 2024, Tshisekedi described it as “a provocation in very bad taste”.

In any case, a ceasefire between the DRC and the M23 is not enough. What is needed is a long-term, durable solution that addresses the root causes and fears that are driving the armed conflict. Läs mer…

Chinese people around the world have just celebrated lunar new year, which this year has run from January 28 to February 4. It is the biggest festival of the year in China, signalling the start of spring, and this is the year of the wood snake. According to Chinese astrology, the characteristics of the snake – renewal, potential, opportunity and wisdom – will affect the year ahead.

As we start the new lunar year, it feels like a good time to look ahead to look at the prospects for the Chinese economy through the prism of these characteristics.

Renewal of traditional economic drivers

China dominates global manufacturing – its manufacturing production is as large as the next seven largest competitors combined. This has earned China the title of the world’s manufacturing superpower – but it has come at a cost. The latest data shows that China is among the top 20 most polluted countries across the world.

Therefore, it’s likely that over the next 12 months, there will be a continued drive towards the renewal, or upgrading, of traditional industrial sectors that have historically driven growth in China but are also heavy polluters.

This is part of a broader push by China to improve its climate footprint and reduce emissions. These are goals outlined in the national climate action plan, referred to by the Paris climate agreement as the nationally determined contributions.

Potential for a surge into AI

China has identified the potential for adopting AI, robotics and 3D printing in transforming its manufacturing base. Meanwhile, the country’s next generation AI development plan sets out clear objectives to make AI the main driver of Chinese economic change and industrial development. Expect to see more progress towards this goal in 2025.

China’s machine-learning sector has experienced considerable growth, and is predicted to grow by an average of 34.8% a year over the next five years. While the US is the major competitor and commands the largest market size, the recent release of the R1 chatbot by DeepSeek has created a stir.

New year, new opportunities.
EPA-EFE/Jessica Lee

DeepSeek claims to have developed its latest R1 model at a cost of around US$6 million (£4.8 million), which is considerably less than its US competitors such as Open AI’s ChatGPT-4, which is reported to have cost more than US$100 million. It’s an indication of the strength of innovation which underlines the potential growth of China’s AI sector, and is likely to help narrow the gap with the US.

Opportunities for foreign investment

In addition to upgrading traditional industries, we can expect to see opportunities around new areas of growth in advanced technology sectors such as fintech and green tech. China will continue shifting its focus to industries in which its firms can add lots of value, such as in technology-related manufacturing.

Major investment is needed to fund these industries and two major changes have occurred in recent months, recognising that this cannot come only from domestic sources.

First, the changes to China’s A-share market, which went into effect in December 2024, will make it easier for a wider range of overseas investors to enter. For example, smaller amounts of capital are required, and foreign capital can now come from unlisted companies.

Second, in November 2024, China opened up its manufacturing sector to foreign capital by removing all access restrictions.

Over the next year, we can expect to see these changes increase the amount of foreign capital in China, and help realise these new areas of growth.

The wisdom of opening up

China continues to see the wisdom of opening its economy in terms of investment – and therefore that it is critically important to remain well-connected to the rest of the world.

The geopolitical tensions with the US are a challenge: the US president, Donald Trump, has said he will impose tariffs of 10% on imports from China. But on a more positive note, breaking protocol last month, Chinese vice-president Han Zheng was invited to, and attended, Trump’s inauguration ceremony.

It’s an indication of the current US administration’s view of the importance of America’s relationship with China.

China’s vice-president, Han Zheng, sits behind media tycoon Rupert Murdoch at Donald Trump’s inauguration, January 2025.
EPA-EFE/Chip Somodevilla/pool

The year ahead is also likely to bring opportunities for the UK to continue its efforts to reset its relationship with China. During the recent visit to Beijing by the chancellor of the exchequer, Rachel Reeves, there was a discussion of a “stable and balanced UK-China relationship”.

Few expect, or desire, a return to the “golden era” rhetoric of the likes of former UK chancellor George Osborne, who in a speech at the Shanghai Stock Exchange in September 2015 called for Britain and China to work together to ensure mutual prosperity: “Let’s stick together to make Britain China’s best partner in the west. Let’s stick together and create a golden decade for both of our countries.”

However, greater dialogue with China may be possible, while at the same time carefully managing the UK’s relationship with the new US administration.

China watchers will be keeping their eyes peeled for other economic developments over the year ahead – for example, the progress of Chinese fiscal reforms and their impact on local and regional finances and income distribution. Also, there is the matter of the real estate market. After significant falls in housing sales and investment during 2024, house prices are showing signs of stabilising.

China’s economy will face challenges in the year ahead. But there are also some clear opportunities for this manufacturing giant, particularly in the tech sector as it starts to narrow the gap with the US. Läs mer…

Restless legs syndrome (RLS), also known as Willis-Ekbom Disease, is a neurological condition that affects about 7% of people.

Typical symptoms include an irresistible urge to move your legs, alongside sensations of aching, crawling, creeping, itching, pulling or throbbing. Until the age of 35, the condition is equally common in men and women, but after that age, RLS affects twice the number of women than men.

Each person’s condition is categorised as mild, moderate, severe or very severe according to the international rating scale, which measures the effects of RLS on limb discomfort and sleep disruption, as well as frequency of symptoms.

RLS symptoms have a 24-hour cycle known as a circadian rhythm. Symptoms tend to peak at night, coinciding with the body’s increase in melatonin release. Melatonin reduces dopamine – the brain chemical that affects movement and mood – to help us sleep but, because dopamine helps control muscles, low dopamine levels can cause involuntary movements.

There is no test for RLS. Diagnosis is based on symptoms and medical history. Primary RLS runs in families – there are genetic links to a number of chromosomes. RLS has an autosomal dominant inheritance pattern, meaning you only need one “defective” copy to present with symptoms. Some cases, however, develop with no known cause.

Other people may develop “secondary” RLS as a result of other conditions, such as iron deficiency anaemia, chronic kidney disease, diabetes, Parkinson’s disease, rheumatoid arthritis, underactive thyroid gland, and fibromyalgia. While primary RLS is more common than secondary, the latter is usually more severe and progresses more rapidly.

Risk factors

Age seems to be a risk factor for RLS. In 2000, a study found that 10% of adults aged 30 to 79 have RLS, increasing to 19% of those over the age of 80. However, understanding of the condition has improved since that study was conducted, so it’s likely these figures are higher – particularly in children, where some RLS symptoms have been confused with “growing pains” or ADHD in the past.

Women have an increased chance of developing RLS. Approximately one in five women will suffer from restless legs at some point, and some studies suggest as many as one in three women are affected. Women are more likely to suffer from other comorbidities that affect the central nervous system, such as anxiety, depression and migraine, which may be linked to the development of RLS.

Pregnancy is another risk factor. The further you are through the trimesters, the higher your chance of being affected BY RLS – with 8%, 16% and 22% of women suffering through their respective first, second and third trimesters. Multiple pregnancies increase the risk of pregnancy-related RLS, and research has found that women who’ve given birth may have a higher incidence of RLS in later life, compared with women of the same age who haven’t given birth.

Obesity is also considered a risk factor for RLS. One study showed that each 5kg/m² increase in body mass index increased the likelihood of developing RLS by 31%.

Triggers and treatments

Research has shown smoking and alcohol consumption seem to make RLS worse, so lifestyle changes such as stopping smoking and drinking alcohol can help manage symptoms.

Research has also found that exercise and stretching is beneficial for symptom relief or reduction – although study participants suggest that morning exercise is more effective for improving symptoms, while evening exercise can make restless legs worse. Patients with secondary forms of RLS, lower BMI and less severe cases of the condition may benefit the most from lifestyle changes to manage symptoms.

Also, treatment of underlying issues can also alleviate or reduce some of the symptoms. For instance, iron deficiency anaemia reduces dopamine levels, which can lead to restless legs. Iron supplements may benefit some sufferers – but the evidence is mixed so supplements won’t help everyone.

In terms of medication, research has found that neurological therapies, such as the anticonvulsant Gabapentin – usually prescribed as a treatment for epilepsy – can improve symptoms and overall quality of life for those suffering with restless legs. These therapies target nerve cells in the brain, reducing their activity.

Other medicines – known as dopamine agonists – activate dopamine receptors in the brain to control movement. They are primarily used as a treatment for Parkinson’s disease and are effective in managing symptoms of RLS. However, they can disturb your sleep pattern and may increase impulse control disorders, and are not recommended during pregnancy or breastfeeding as they can inhibit lactation.

While there may not be a cure for RLS, there is hope for sufferers – and options for managing and reducing symptoms. Läs mer…

Observing Greenland from a helicopter, the main problem is one of comprehending scale. I have thought we were skimming low over the waves of a fjord, before noticing the tiny shadow of a seabird far below and realising what I suspected were floating shards of ice were in fact icebergs the size of office blocks. I have thought we were hovering high in the sky over a featureless icy plane below, before bumping down gently onto ice only a few metres below us.

Crevasses – cracks in the surface of glaciers – are the epitome of this baffling range of scales. Formed by stresses at the surface, their direction and size tell us how the ice sheet is flowing towards the ocean. Inland, far away from the fast-flowing glaciers that discharge hundreds of gigatonnes of icebergs a year into fjords, crevasses can be tiny cracks only millimetres wide.

As the ice speeds up, they can be metres in diameter, sometimes covered by deceptive snow bridges that require suitable safety equipment and rescue training to traverse. Finally, where the ice meets the ocean and no scientist would ever dare to stand, they can be monsters over 100 metres from wall to wall. And across Greenland, they are growing.

Cracks you could fly a helicopter through.
Tom Chudley

It shouldn’t be particularly surprising to scientists that crevasses are getting larger across Greenland. As the ocean warms, the ice sheet has sped up in response, increasing the stresses acting upon its surface. However, observations from satellites and in-person fieldwork are so poor that to date, we had no idea how extensively or quickly this process has been occurring.

Mapping cracks

In a new study, my colleagues and I mapped crevasses across the entirety of the Greenland ice sheet in 2016 and 2021. To do this, we used the “ArcticDEM”: three-dimensional surface maps of the polar regions based on high resolution satellite images. By applying image-processing techniques to over 8,000 maps, we could estimate how much water, snow or air would be needed to “fill” each crevasse across the ice sheet. This enabled us to calculate their depth and volume, and examine how they evolved.

We found that from 2016 to 2021, there were significant increases in crevasse volume across fast-flowing sectors of the Greenland ice sheet. In the southeast of the ice sheet, an area that has been particularly vulnerable to ocean-induced acceleration and retreat in the past few years, crevasse volume increased by over 25%.

In most Greenland glaciers that flow into the ocean, scientists found crevasses are increasing in size and depth.
Chudley et al / Nature Geoscience

However, against our expectations, crevasse volume across the whole ice sheet increased by only 4.3%. That’s much closer to an overall balance than the extremes observed in certain sectors. What had happened? In fact, the significant increases elsewhere were being offset by a single source: an outlet glacier known as Sermeq Kujalleq (Danish: Jakobshavn Isbræ).

Sermeq Kujalleq is the fastest-flowing glacier on the planet, reaching speeds of nearly 50 metres a day and providing an outsized proportion of Greenland’s total sea-level rise contribution. In 2016, responding to an influx of cold water from the north Atlantic ocean, the glacier slowed and thickened. As it did this, the crevasses on the surface began to close – offsetting increases across the rest of the ice sheet.

This slowdown was short-lived. Since 2018, Sermeq Kujalleq has once again reverted to acceleration and thinning in response to ongoing warming. We won’t be able to rely on it to offset ice-sheet-wide increases in crevassing in the future.

Cracks grow into icebergs

Crevasses play an integral part in the life cycle of glaciers, and as they grow they hold the potential to further accelerate ice-sheet loss. They deliver surface meltwater into the belly of the ice sheet: once inside, water can act to warm the ice or lubricate the bed that the glacier slides over, both of which can make the ice sheet flow faster into the ocean. Meanwhile, where the ice meets the sea, crevasses form the initial fractures from which icebergs can break off, increasing the output of icebergs into the ocean.

Where Sermeq Kujalleq, or Jakobshavn Glacier, meets the sea. That iceberg filled fjord is several miles wide.
Copernicus Sentinel / lavizzara / shutterstock

In short, crevasses underpin the dynamic processes that occur across Greenland and Antarctica. However, these processes are very poorly understood, and their future evolution is the single largest uncertainty in our predictions of sea-level rise. Together, the increased discharge of ice holds the potential to add up to 10 metres of additional sea-level rise by 2300 (75% of all cities with more than 5 million inhabitants exist less than 10m above sea level). We need to better understand these processes – including crevasses – so that informed sea-level projections can form the basis of our responses to the global challenges that climate change presents.

Since 2023, an international coalition of polar scientists has been urging the world to limit warming to 1.5˚C to avoid the most catastrophic melt scenarios for global glaciers and ice sheets. Last month, the EU’s Copernicus Climate Change Service confirmed that 2024 was the first year in which average global temperatures exceeded this threshold.

Every fraction of a degree matters. We may still be able to save ourselves from the worst of the damage the climate change will bring – but we are desperately running out of time.

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Humans have an exceptional ability to deal with viruses. In most cases, your immune system is able to fight an infection. On the other hand, your body provides a spa-like environment that is temperate and stable, optimal for viruses to replicate. Human behavior, including close contact with animals and frequent travel, also increases the likelihood of becoming infected.

From the perspective of viruses spread by insects, or arboviruses, making the evolutionary leap from insects to humans is a tough battle. Viruses cannot replicate very well in humans, which means transmission from mosquitoes is often very difficult.

One might think arboviruses continually evolve in ways that enable them to infect more species. But do they?

We are a virologist and an entomologist who study insect-borne and viral diseases and how human and insect immune systems respond to invading pathogens. Our work provides insights on the complex journey of an arbovirus as it cycles between insect and vertebrate hosts.

As an example, let’s use a Togavirus, the mosquito-transmitted arbovirus that causes eastern equine encephalitis, or EEE. This rare but serious disease can cause a potentially fatal neurological condition in humans and horses. Although EEE is primarily endemic to the eastern United States, its incidence in recent years has increased in regions farther north, with several reported cases in states such as Michigan, Massachusetts and New York.

While rare, a EEE infection in people can lead to severe complications or death.

From animals to mosquitoes

A female mosquito’s inner workings – particularly its guts and salivary glands – create the perfect environment for a virus to flourish.

When a mosquito bites an infected nonhuman host, such as a sick bird, the virus is transported with freshly ingested blood into the mosquito’s midgut – the equivalent to the human stomach and intestines where food is stored and digested. The virus quickly infects midgut cells to avoid a hostile digestive environment and quietly replicates without activating the mosquito’s immune pathways.

Within days, the virus will be released by damaged midgut cells to migrate to the mosquito’s salivary glands, where it will be positioned for transmission. Now, each time the mosquito feeds, it will pump virus-saturated saliva into its new animal host and continue the disease transmission cycle.

This image shows a tissue section of the salivary gland of a mosquito infected with EEE. The virus particles are colored red.
Fred Murphy and Sylvia Whitfield/CDC

It is easy for the virus to avoid detection by the mosquito’s relatively primitive immune system. Compared with humans, the immune system of mosquitoes can launch only a generalized and overall less effective attack on pathogens. This means an arbovirus can usually establish a persistent, lifelong, almost symbiotic infection without damaging the mosquito’s health, perfect for the virus to disseminate itself.

Mosquitoes have evolved over millions of years to become tolerant to arboviral infections. This relationship has allowed the mosquito to maintain viral populations without having to launch energy-expensive immune responses. However, this does not mean mosquitoes are just passive virus carriers. An arbovirus can change how infected mosquitoes behave or reproduce.

For example, viruses can manipulate mosquitoes in two ways: by making them feed more frequently, and by increasing their attraction to infected hosts. However, this behavior puts the mosquito at greater risk of being killed by irritated hosts who notice the repeated biting attempts. Arboviruses can also affect mosquito reproduction by sometimes reducing the number of eggs a female mosquito produces and increasing the length of time it takes for the eggs to mature. In some cases, these viruses can even sterilize female mosquitoes.

Arboviruses have evolved to expertly use mosquitoes as both transportation vehicles and breeding grounds. By spreading and multiplying without severely harming their insect hosts, these viruses ensure their own survival and continued transmission.

From mosquitoes to humans

The virus must overcome several barriers to successfully colonize a human host.

The initial step for successful disease transmission – the virus’s ultimate goal – is perhaps the easiest: The EEE virus infects humans when a virus-infected female mosquito has an unquenchable appetite for warm blood. From the moment the virus is deposited under the skin through the mosquito’s infected saliva, a tough battle ensues.

The first battle for the virus is to adapt to a typically much hotter setting than the ambient environment – the human body temperature of around 98.6 degrees Fahrenheit (37 degrees Celcius) or higher.

Then, the virus must evade the host’s immediate defenses, which includes physical barriers, such as layers of skin and mucosa, as well as immune cells that detect and attack invading microbes. Once in the bloodstream, the virus faces the adaptive arm of the human immune system, which is capable of targeting specific viral components with exquisite precision, like a biological sniper.

Once the EEE virus reaches the central nervous system – the brain and spinal cord – the immune system can overreact to the infection and inadvertently cause inflammation and damage nerve cells. This can lead to serious long-term effects, such as cognitive impairment.

The human immune response is more robust than that of a mosquito.
Sashunita/Cavan Images via Getty Images

To persist in this hostile human environment, the virus uses various survival strategies. One technique is creating new mutations on its surface and shape-shifting to avoid immune detection. Another strategy is to hijack human cells to replicate itself, such as using the cell’s machinery to synthesize new viral components and altering how the cell regulates division.

As viruses adapt to overcome immune defenses, both humans and mosquitoes evolve countermeasures to fight infection. The greater complexity of the human immune system makes it especially challenging for viruses to survive and spread between human hosts.

From human to human?

Like many other arboviruses, the EEE virus cannot be transmitted from person to person, which effectively limits its spread among human populations. Your body keeps the virus contained. Consequently, when the EEE virus infects people via the bite from an infected mosquito, it is considered a dead end, as it cannot escape its human host or infect another bloodthirsty mosquito.

So, what does the virus that causes EEE gain by infecting people? Not likely anything. A mosquito-borne virus like the Togavirus that causes EEE prefers its established transmission cycle between mosquitoes and birds. Human infections occur only when a mosquito deviates from its typical menu of birds.

EEE spreads more easily between mosquitoes and birds than it does in humans, which helps explain why human infections don’t happen very often. Thankfully, human bodies simply aren’t the virus’s currently preferred environment. Läs mer…

The colors of rubies and emeralds are so striking that they define shades of red and green – ruby red and emerald green. But have you ever wondered how they get those colors?

I am an inorganic chemist. Researchers in my field work to understand the chemistry of all the elements that make up the periodic table. Many inorganic chemists focus on the transition metals – the elements in the middle of the periodic table. The transition metals include most of the metals you are familiar with, like iron (Fe) and gold (Au).

One feature of compounds made with transition metals is their intense color. There are many examples in nature, including gemstones and paint pigments. Even the color of blood comes from the protein hemoglobin, which contains iron.

Investigating the colors of compounds containing transition metals leads you into some really amazing science – that’s part of what drew me to study this field.

Rubies and emeralds are great examples of how a small amount of a transition metal – in this case, chromium – can create a beautiful color in what would otherwise be a fairly boring-looking mineral.

Minerals and crystals

Rubies appear red because they absorb blue and green light.
benedek/E+ via Getty Images

Both rubies and emeralds are minerals, which is a type of rock with a consistent chemical composition and a highly ordered structure at the atomic level.

When this highly ordered structure extends in all three dimensions, the mineral becomes a crystal.

With a theory developed by physicists in the 1920s called crystal field theory, scientists can explain why rubies and emeralds have the colors they do. Crystal field theory makes predictions about how a transition metal ion’s structure is affected by the other atoms surrounding it.

Rubies are mainly made up of the mineral corundum, which is composed of the elements aluminum and oxygen in a regular, repeating array. Each aluminum ion is surrounded by six oxygen ions.

A crystal of corundum looks like this at the atomic level, with the aluminum ions shown as red balls and the oxygen ions shown as white balls. Each aluminum ion is surrounded by six oxygen ions, and each oxygen by four aluminums.
Eigenes Werk/Wikimedia Commons, CC BY-SA

Emeralds are mainly made up of the mineral beryl, which is made from the elements beryllium, aluminum, silicon and oxygen. Beryl’s crystal structure is more complicated than corundum’s because of the additional elements in the formula, but each aluminum ion is again surrounded by six oxygen ions.

Emeralds appear green because they absorb red and blue light.
SunChan/E+ via Getty Images

Pure corundum and beryl are colorless. The brilliant colors of rubies and emeralds come from the presence of very small amounts of chromium. The chromium replaces about 1% of the aluminum in the corundum or beryl crystal when a ruby or emerald forms underground at a high temperature and pressure.

But how can one element – chromium – create the red color of a ruby and green color of an emerald?

Color science

Rubies and emeralds have the colors they do because, like many substances, they absorb some colors of light. Most visible light, like sunlight, is composed of all the colors of the rainbow: red, orange, yellow, green, blue, indigo and violet. These colors make up the visible light spectrum, which is easy to remember as ROY G BIV.

Objects absorb some visible light wavelengths and reflect others, which is why we see them as having a color.
Fulvio314/Wikimedia Commons, CC BY-SA

One of the main reasons why objects have a color is because they absorb one or more of these visible colors of light. If a substance absorbs, for instance, red light, it means that the red light gets trapped in the substance and the other colors reflect back to your eyes. The color you see is the sum of the remaining light, which will be in the green-to-blue range. If a substance absorbs blue, it will look red or orange to you.

Unlike the colorless aluminum ion, the chromium ion absorbs blue and green light when surrounded by the oxygen ions. The red light is reflected back, so that’s what you see in rubies.

In an emerald, even though the chromium is surrounded by six oxygen ions, there is a weaker interaction between the chromium and the surrounding oxygen ions. That’s due to the presence of silicon and beryllium in the beryl crystal. They cause the emerald to absorb blue and red light, leaving the green for you to see.

The ability to tune the properties of transition metals like chromium through changing what is surrounding it is a core strategy in my field of inorganic chemistry. Doing so can help scientists understand the basic science of metal-containing compounds and the design of chemical compounds for specific purposes.

You can take delight in the amazing colors of the gemstones, but through chemistry, you can also see how nature creates those colors using an endless variety of complex structures made with the elements in the periodic table. Läs mer…